Alzheimer's - Brain Death, a Metabolic disease driven by Lifestyle and Diet.
It's all about Energy, as current evidence shows that our brain size increased 350% [Brain] and blood flow to the brain increased 600%, [Brain Energy] clearly indicating our brain's energy requirements. With our large brain using 20% of metabolic energy and more when sleeping (Circadian Rhythm and Time-Restriced Feeding, TRF) our metabolism needed to produce more energy for our complex bodily systems and complex thinking. (Note 1)
In addition, this bodily change to a higher energy requirement and sourcing, allowed for smaller intestines, better immune system, more reproduction, more time for hunting and social contact, and bigger brains. The brain is extremely expensive in metabolic terms, and uses about 20% of food calories. Humans have the biggest brain and the smallest gut among primates. (1,2)
Anatomy of the Body's Energy: The brain, heart, liver, and kidneys consume about 60% of the body’s energy intake thereby dominating resting human energy metabolism. The heart and kidneys are metabolically more active than the brain but, being larger, the brain takes a higher proportion of the body’s total energy needs, i.e. about 20–23% of the body’s total energy requirement despite representing only 2.0–2.3% of adult body weight (3,4,5). Three major parameters linked to brain energy metabolism – cerebral blood flow, oxygen consumption, glucose and ketone metabolism - can all be measured independently in humans using minimally invasive techniques. (6,7)
Emerging evidence indicates that impaired cellular energy metabolism is the defining characteristic of nearly all modern diseases, i.e. Man-made.
Essentially these man-made diseases are all hallmarks of insulin overload manifested as Dr. Raven's
Syndrome X. (8,9)
Ref: ... Insulin Resistance - root cause of Chronic Inflammation.
Half of what we know is wrong, the purpose of science is to determine which half " ... Arthur Kornberg, Nobel Laureate - DNA, "The Nobel Prize in Physiology or Medicine 1959"
Alzheimer's is now being called Type 3 Diabetes by some doctors. According to
Dr. Georgia Ede - Diagnosis: Diet and Preventing Alzheimer's -, she
points out that 80% of Alzheimer's patients have
Insulin Resistance - or full blown Type 2 diabetes. Preventing Alzheimer’s disease Is easier than
we think as researchers now understand that insulin resistance is a powerful force in the development of Alzheimer’s Disease.
Dr. Ede explains ...
It’s more accurate to think of it this way: Insulin resistance of the body is type 2 diabetes; insulin resistance of the brain is type 3 diabetes.
They are two separate diseases caused by the same underlying problem: Chronic Insulin Resistance.
Mounting research also suggests Alzheimer’s (Diabetes of the Brain - Type 3) disease is intricately connected to
Insulin Resistance; even mild elevation of blood sugar is
associated with an elevated risk for dementia (mean age baseline was 76 - higher average glucose levels within the preceding 5 years were related to an increased risk of dementia ). (10)
Diabetes and heart disease also elevate your risk, as all three conditions are rooted in
Chronic Insulin Resistance.
Say NO to Sugar and get your
The brain is made almost entirely of fat (57%) (50% fat by dry weight), and protein (38%), and contains very little carbohydrate (5%). From
Dr. Cate Shanahan's book
we also know that the ratio of
Omega-3 to Omega-3 is 1:1 in the Brain, hence dietary shortages or the wrong dietary intake of fats and oils will change our
Ref: ... this site - Lipids and the Centenarian Diet, and Dr. Cate's recommendations.
Our modern brains grew up in a low glycemic index environment. For 2 million years of our evolution,
we ate much less carbohydrate than we do now, and certainly no refined or processed carbohydrates.
The brain needs blood sugar and insulin levels to be nice and even in order to keep brain chemistry stable.
The Real Rub - we were never designed to use carbs as fuel. Also ref: ... Carb-Loading (debunked).
Importance/benefits of fat and ketone bodies (Ketosis) in the Brain.
Saturated Fat. 11% arachidonic acid and 25% of fatty acids making up the brain neurons and cells, are DHA - Omega-3. Ref: ... Fats and Oil - Where did the Omega-3s Go? | contributor april/2016. (11)
pure mathit can be shown why
Water Absorption Properties, i.e. Hydrophilic.
Good News - the brain has the ability to reorganize itself by forming new neural connections throughout life. Neuroplasticity allows the neurons (nerve cells) in the brain to compensate for injury and disease and to adjust their activities in response to new situations or to changes in their environment.
However: we are now seeing
New Diseases created by malnutrition and excessive intake of carbohydrates, i.e.
Excess Carbohydrates is Malnutrition.
Chronic Inflammation is leading us into the realm of Type 2 diabetes and Alzheimer's.
TBD, ... but you can read
Dr. Dale E. Bredesen's book - The End of Alzheimer's
or Amy Berger's Book- The Alzheimer's Antidote
Ketone Fuelwill protect the Brain by a shift away from man-made Hyper-Palatable Foods.
Dr. Tan is introducing Veterans with advanced cancer to a ketogenic LCHF - (high-fat, adequate-protein, low-carbohydrate) diet. This eating plan starves cancer cells while still meeting a patient's nutritional needs.Take Action
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